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Myelin oligodendrocyte glycoprotein associated transverse myelitis following brain abscess: Case report and literature review

Published:September 05, 2022DOI:https://doi.org/10.1016/j.jneuroim.2022.577967

      Abstract

      Transverse myelitis is a subacute immune mediated myelopathy secondary to a range of conditions. Post infectious transverse myelitis can be seen with several infectious etiologies. Myelin oligodendrocyte glycoprotein associated disease (MOGAD) is a relatively recently defined condition frequently manifesting with longitudinally extensive transverse myelitis. Cases of MOGAD have occurred after infection, typically respiratory tract infections. We report an unusual case of MOGAD transverse myelitis following a streptococcal brain abscess which has not been previously reported.

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      References

        • Akaishi T.
        • Misu T.
        • Fujihara K.
        • et al.
        Relapse activity in the chronic phase of anti-myelin-oligodendrocyte glycoprotein antibody-associated disease [published online ahead of print, 2021 Nov 25].
        J. Neurol. 2021; https://doi.org/10.1007/s00415-021-10914-x
        • Chen J.J.
        • Flanagan E.P.
        • Bhatti M.T.
        • et al.
        Steroid-sparing maintenance immunotherapy for MOG-IgG associated disorder.
        Neurology. 2020; 95: e111-e120https://doi.org/10.1212/WNL.0000000000009758
        • Chen J.J.
        • Huda S.
        • Hacohen Y.
        • Levy M.
        • Lotan I.
        • Wilf-Yarkoni A.
        • Stiebel-Kalish H.
        • Hellmann M.A.
        • Sotirchos E.S.
        • Henderson A.D.
        • Pittock S.J.
        • Bhatti M.T.
        • Eggenberger E.R.
        • Di Nome M.
        • Kim H.J.
        • Kim S.H.
        • Saiz A.
        • Paul F.
        • Dale R.C.
        • Ramanathan S.
        • Palace J.
        • Camera V.
        • Leite M.I.
        • Lam B.L.
        • Bennett J.L.
        • Mariotto S.
        • Hodge D.
        • Audoin B.
        • Maillart E.
        • Deschamps R.
        • Pique J.
        • Flanagan E.P.
        • Marignier R.
        Association of maintenance intravenous immunoglobulin with prevention of relapse in adult myelin oligodendrocyte glycoprotein antibody-associated disease.
        JAMA Neurol. 2022 May 1; 79 (PMID: 35377395; PMCID: PMC8981066): 518-525https://doi.org/10.1001/jamaneurol.2022.0489
        • Ciron J.
        • Cobo-Calvo A.
        • Audoin B.
        • et al.
        Frequency and characteristics of short versus longitudinally extensive myelitis in adults with MOG antibodies: a retrospective multicentric study.
        Mult. Scler. 2020; 26: 936-944https://doi.org/10.1177/1352458519849511
        • de Seze J.
        • Stojkovic T.
        • Breteau G.
        • Lucas C.
        • Michon-Pasturel U.
        • Gauvrit J.Y.
        • Hachulla E.
        • Mounier-Vehier F.
        • Pruvo J.P.
        • Leys D.
        • Destée A.
        • Hatron P.Y.
        • Vermersch P.
        Acute myelopathies: clinical, laboratory and outcome profiles in 79 cases.
        Brain. 2001 Aug; 124 (PMID: 11459743): 1509-1521https://doi.org/10.1093/brain/124.8.1509
        • Durozard P.
        • Rico A.
        • Boutiere C.
        • et al.
        Comparison of the response to rituximab between myelin oligodendrocyte glycoprotein and Aquaporin-4 antibody diseases.
        Ann. Neurol. 2020; 87: 256-266https://doi.org/10.1002/ana.25648
        • Huda S.
        • Whittam D.
        • Jackson R.
        • et al.
        Predictors of relapse in MOG antibody associated disease: a cohort study.
        BMJ Open. 2021; 11 (e055392. Published 2021 Nov 30)https://doi.org/10.1136/bmjopen-2021-055392
        • Jarius S.
        • Ruprecht K.
        • Kleiter I.
        • et al.
        MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome.
        J Neuroinflammat. 2016; 13 (Published 2016 Sep 27): 280
        • Jurynczyk M.
        • Messina S.
        • Woodhall M.R.
        • et al.
        Clinical presentation and prognosis in MOG-antibody disease: a UK study [published correction appears in brain. 2018 Apr 1;141(4):e31].
        Brain. 2017; 140: 3128-3138https://doi.org/10.1093/brain/awx276
        • Nakamura M.
        • Iwasaki Y.
        • Takahashi T.
        • Kaneko K.
        • Nakashima I.
        • Kunieda T.
        • Kaneko S.
        • Kusaka H.
        A case of MOG antibody-positive bilateral optic neuritis and meningoganglionitis following a genital herpes simplex virus infection.
        Mult Scler Relat Disord. 2017 Oct; 17 (Epub 2017 Jul 27. PMID: 29055448.Kakalacheva K, Regenass S, Wiesmayr S, Azzi T, Berger C, Dale RC, Brilot F, Münz C, Rostasy K, Nadal D, Lünemann JD. Infectious Mononucleosis Triggers Generation of IgG Auto-Antibodies against Native Myelin Oligodendrocyte Glycoprotein. Viruses. 2016 Feb 12;8(2):51. doi: https://doi.org/10.3390/v8020051. PMID: 26907324; PMCID: PMC4776206): 148-150https://doi.org/10.1016/j.msard.2017.07.023
        • Nakamura Y.
        • Nakajima H.
        • Tani H.
        • Hosokawa T.
        • Ishida S.
        • Kimura F.
        • Kaneko K.
        • Takahashi T.
        • Nakashima I.
        Anti-MOG antibody-positive ADEM following infectious mononucleosis due to a primary EBV infection: a case report.
        BMC Neurol. 2017 Apr 19; 17 (PMID: 28420330; PMCID: PMC5395865): 76https://doi.org/10.1186/s12883-017-0858-6
        • Netravathi M.
        • Dhamija K.
        • Gupta M.
        • Tamborska A.
        • Nalini A.
        • Holla V.V.
        • Nitish L.K.
        • Menon D.
        • Pal P.K.
        • Seena V.
        • Yadav R.
        • Ravindranadh M.
        • Faheem A.
        • Saini J.
        • Mahadevan A.
        • Solomon T.
        • Singh B.
        COVID-19 vaccine associated demyelination & its association with MOG antibody.
        Mult Scler Relat Disord. 2022 Apr; 60 (Epub 2022 Mar 13. PMID: 35306244; PMCID: PMC8917969): 103739https://doi.org/10.1016/j.msard.2022.103739
        • Ramanathan S.
        • Mohammad S.
        • Tantsis E.
        • Nguyen T.K.
        • Merheb V.
        • Fung V.S.C.
        • White O.B.
        • Broadley S.
        • Lechner-Scott J.
        • Vucic S.
        • Henderson A.P.D.
        • Barnett M.H.
        • Reddel S.W.
        • Brilot F.
        • Dale R.C.
        Australasian and New Zealand MOG Study Group. Clinical course, therapeutic responses and outcomes in relapsing MOG antibody-associated demyelination.
        J. Neurol. Neurosurg. Psychiatry. 2018 Feb; 89 (Epub 2017 Nov 15. PMID: 29142145; PMCID: PMC5800335): 127-137https://doi.org/10.1136/jnnp-2017-316880
        • Ramanathan S.
        • Mohammad S.
        • Tantsis E.
        • Nguyen T.K.
        • Merheb V.
        • Fung V.S.C.
        • White O.B.
        • Broadley S.
        • Lechner-Scott J.
        • Vucic S.
        • Henderson A.P.D.
        • Barnett M.H.
        • Reddel S.W.
        • Brilot F.
        • Dale R.C.
        Australasian and New Zealand MOG Study Group. Clinical course, therapeutic responses and outcomes in relapsing MOG antibody-associated demyelination.
        J. Neurol. Neurosurg. Psychiatry. 2018 Fe; 89 (Epub 2017 Nov 15. PMID: 29142145; PMCID: PMC5800335): 127-137https://doi.org/10.1136/jnnp-2017-316880
        • Ringelstein M.
        • Ayzenberg I.
        • Lindenblatt G.
        • Fischer K.
        • Gahlen A.
        • Novi G.
        • Hayward-Könnecke H.
        • Schippling S.
        • Rommer P.S.
        • Kornek B.
        • Zrzavy T.
        • Biotti D.
        • Ciron J.
        • Audoin B.
        • Berthele A.
        • Giglhuber K.
        • Zephir H.
        • Kümpfel T.
        • Berger R.
        • Röther J.
        • Häußler V.
        • Stellmann J.P.
        • Whittam D.
        • Jacob A.
        • Kraemer M.
        • Gueguen A.
        • Deschamps R.
        • Bayas A.
        • Hümmert M.W.
        • Trebst C.
        • Haarmann A.
        • Jarius S.
        • Wildemann B.
        • Grothe M.
        • Siebert N.
        • Ruprecht K.
        • Paul F.
        • Collongues N.
        • Marignier R.
        • Levy M.
        • Karenfort M.
        • Deppe M.
        • Albrecht P.
        • Hellwig K.
        • Gold R.
        • Hartung H.P.
        • Meuth S.G.
        • Kleiter I.
        • Aktas O.
        • Neuromyelitis Optica Study Group (NEMOS)
        Interleukin-6 receptor blockade in treatment-refractory MOG-IgG-associated disease and neuromyelitis optica spectrum disorders.
        Neurol Neuroimmunol Neuroinflamm. 2021 Nov 16; 9 (e1100. PMID: 34785575; PMCID: PMC8596357)https://doi.org/10.1212/NXI.0000000000001100
        • Rojas M.
        • Restrepo-Jiménez P.
        • Monsalve D.M.
        • Pacheco Y.
        • Acosta-Ampudia Y.
        • Ramírez-Santana C.
        • Leung P.S.C.
        • Ansari A.A.
        • Gershwin M.E.
        • Anaya J.M.
        Molecular mimicry and autoimmunity.
        J. Autoimmun. 2018 Dec; 95 (Epub 2018 Oct 26. PMID: 30509385): 100-123https://doi.org/10.1016/j.jaut.2018.10.012
        • Sechi E.
        • Buciuc M.
        • Pittock S.J.
        • et al.
        Positive predictive value of myelin oligodendrocyte glycoprotein autoantibody testing.
        JAMA Neurol. 2021; 78: 741-746https://doi.org/10.1001/jamaneurol.2021.0912
        • Williams T.
        • Thorpe J.
        Post-infective transverse myelitis following Streptococcus pneumoniae meningitis with radiological features of acute disseminated encephalomyelitis: a case report.
        J. Med. Case Rep. 2012; 6 (Published 2012 Sep 19): 313
        • Zalewski N.L.
        • Flanagan E.P.
        • Keegan B.M.
        Evaluation of idiopathic transverse myelitis revealing specific myelopathy diagnoses.
        Neurology. 2018 Jan 9; 90 (Epub 2017 Dec 15. PMID: 29247071): e96-e102https://doi.org/10.1212/WNL.0000000000004796