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Editorial Board
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iii
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| Reviews |
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Hemispheric lateralisation and immune function: A systematic review of human research
19 September 2011
Abstract: Past studies examined relationships between hemispheric lateralisation (HL) and immune system functioning. However, there has been no up-dated systematic review of this research area. This a...
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Rachel C. Sumner,
Andrew Parton,
Alexander V. Nowicky,
Uday Kishore,
Yori Gidron
et al.
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1-12
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More to come: Humoral immune responses in MS
24 October 2011
Abstract: Interest in the role of B-cells in multiple sclerosis (MS) pathogenesis has increased, and a number of B-cell targeted therapies are currently in clinical trials. B-cells are key mediators o...
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Ruth Dobson,
Ute C. Meier,
Gavin Giovannoni
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13-21
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Role of γδ T cells in West Nile virus-induced encephalitis: Friend or foe?
14 November 2011
Abstract: West Nile virus (WNV)-induced encephalitis has been a public health concern in North America over the past decade. No therapeutics or vaccines are available for human use. Studies in animal ...
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Tian Wang
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22-27
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| Research Papers |
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Antibody response in MOG35–55 induced EAE
12 October 2011
Abstract: Neurological deficit in experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis is widely considered to be a consequence of synergistic T and B cell responses to central nervo...
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Patrice H. Lalive,
Nicolas Molnarfi,
Mahdia Benkhoucha,
Martin S. Weber,
Marie-Laure Santiago-Raber
et al.
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28-33
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Stimulatory effect of antidepressant drug pretreatment on progression of B16F10 melanoma in high-active male and female C57BL/6J mice
28 October 2011
Abstract: The effect of a two-week desipramine or fluoxetine (10mg/kg, i.p.) pretreatment on B16F10 melanoma growth in 3–5month old female and male C57BL/6J mice differing in behavioral characteristic...
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Marta Kubera,
Beata Grygier,
Danuta Wrona,
Zofia Rogóż,
Adam Roman,
Agnieszka Basta-Kaim,
Bogusława Budziszewska,
Monika Leskiewicz,
Danuta Jantas,
Wojciech Nowak,
Michael Maes,
Wladyslaw Lason
et al.
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34-44
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T-bet deficient mice exhibit resistance to stress-induced development of depression-like behaviors
24 October 2011
Abstract: T-bet, a Th1-specific T-box transcription factor, regulates Th1 development by inducing endogenous Th1 cytokines and IFN-γ. This study was conducted to determine if T-bet knockout mice exhib...
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Soo-Jeong Kim,
Hyojung Lee,
Hye-Young Joung,
Gihyun Lee,
Hye-jeong Lee,
Min-Kyu Shin,
Sung-Hoon Kim,
Insop Shim,
Hyunsu Bae
et al.
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45-51
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Cladribine inhibits cytokine secretion by T cells independently of deoxycytidine kinase activity
28 October 2011
Abstract: Cladribine (2-chloro-2′-deoxyadenosine) is a purine nucleoside analogue (PNA) which causes targeted and sustained reduction of peripheral lymphocyte counts. Cladribine tablets produced signi...
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Bruno Laugel,
Frédéric Borlat,
Laurent Galibert,
Alain Vicari,
Robert Weissert,
Yolande Chvatchko,
Denis Bruniquel
et al.
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52-57
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The Gap-junction inhibitor Carbenoxolone suppresses the differentiation of Th17 cells through inhibition of IL-23 expression in antigen presenting cells
31 October 2011
Abstract: Carbenoxolone (CBX) is a widely used gap-junction inhibitor. We have previously shown that treatment with CBX significantly delayed the onset of experimental autoimmune encephalomyelitis (EA...
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Li Endong,
Jin Shijie,
Yoshifumi Sonobe,
Ma Di,
Li Hua,
Jun Kawanokuchi,
Tetsuya Mizuno,
Akio Suzumura
et al.
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58-64
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GM-CSF-induced regulatory T cells selectively inhibit anti-acetylcholine receptor-specific immune responses in experimental myasthenia gravis
18 November 2011
Abstract: We and others have demonstrated the ability of granulocyte-macrophage colony-stimulating factor (GM-CSF) to suppress autoimmunity by increasing the number of CD4+CD25+ regulatory T cells (Tr...
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Jian Rong Sheng,
Thiruppathi Muthusamy,
Bellur S. Prabhakar,
Matthew N. Meriggioli
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65-73
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| Clinical Neuroimmunology |
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Campylobacter jejuni DNA-binding protein from starved cells in Guillain–Barré syndrome patients
13 October 2011
Abstract: Campylobacter jejuni enteritis is frequently associated with an axonal form of Guillain–Barré syndrome (GBS) and C. jejuni DNA-binding protein from starved cells (C-Dps) induces paranodal my...
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Nobutoshi Kawamura,
Hua Piao,
Motozumi Minohara,
Takuya Matsushita,
Susumu Kusunoki,
Hiroshi Matsumoto,
Kazuhiro Ikenaka,
Yoshimitsu Mizunoe,
Jun-ichi Kira
et al.
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74-78
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Development of a highly sensitive diagnostic assay for muscle-specific tyrosine kinase (MuSK) autoantibodies in myasthenia gravis
12 October 2011
Abstract: Autoimmune myasthenia gravis is usually characterized by the presence of autoantibodies against the acetylcholine receptor (~80–90% of patients) or muscle-specific tyrosine kinase (MuSK) (~5...
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Nikolaos Trakas,
Paraskevi Zisimopoulou,
Socrates J. Tzartos
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79-86
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Vitamin D sensitive EBNA-1 specific T cells in the cerebrospinal fluid of patients with multiple sclerosis
24 October 2011
Abstract: The pathogenesis of multiple sclerosis (MS) may involve intrathecal Epstein–Barr virus nuclear antigen-1 (EBNA-1) specific T cells susceptible to modulation by vitamin D. We established EBNA...
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Andreas Lossius,
Frode Vartdal,
Trygve Holmøy
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87-96
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Th17 expansion in MS patients is counterbalanced by an expanded CD39+ regulatory T cell population during remission but not during relapse
28 October 2011
Abstract: In this study, percentages of CD39+ Treg and Th17 cells were compared between relapsing-remitting MS patients and controls and were related to the vitamin D status. The Th17 cell population ...
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Evelyn Peelen,
Jan Damoiseaux,
Joost Smolders,
Stephanie Knippenberg,
Paul Menheere,
Jan Willem Cohen Tervaert,
Raymond Hupperts,
Mariëlle Thewissen
et al.
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97-103
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Cerebrospinal fluid levels of CXCL13 are elevated in neuromyelitis optica
31 October 2011
Abstract: Background: B cells are believed to play an important role in the pathogenesis of NMO. Chemokine (C-X-C motif) ligand 13 (CXCL13), the most potent B-cell chemoattractant, is a chemokine whic...
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Xiaonan Zhong,
Honghao Wang,
Yongqiang Dai,
Aimin Wu,
Jian Bao,
Wen Xu,
Chen Cheng,
Zhengqi Lu,
Wei Qiu,
Xueqiang Hu
et al.
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104-108
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Immune cell NT-3 expression is associated with brain atrophy in multiple sclerosis patients
31 October 2011
Abstract: While neurotrophins mediate cell survival and proliferation in the nervous system, they are also expressed within peripheral blood mononuclear cells (PBMCs) of the immunological system. In m...
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Alicja Kalinowska-Łyszczarz,
Mikołaj A. Pawlak,
Sławomir Michalak,
Włodzimierz Paprzycki,
Jacek Losy
et al.
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109-113
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Galanin and α-MSH autoantibodies in cerebrospinal fluid of patients with Alzheimer's disease
14 November 2011
Abstract: Background: Neuropeptides galanin and α-melanocyte-stimulating hormone (α-MSH) are involved in the regulation of memory and appetite. Increased galanin and decreased α-MSH levels were report...
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Alfredo Costa,
Paola Bini,
Maria Hamze-Sinno,
Arrigo Moglia,
Diego Franciotta,
Elena Sinforiani,
Sabrina Ravaglia,
Christine Bole-Feysot,
Tomas Hökfelt,
Pierre Déchelotte,
Sergueï O. Fetissov
et al.
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114-120
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Human T-cell responses to botulinum neurotoxin. Responses in vitro of lymphocytes from patients with cervical dystonia and/or other movement disorders treated with BoNT/A or BoNT/B
14 November 2011
Abstract: We have previously reported that botulinum neurotoxin type A (BoNT/A)-specific T-cell responses occur in a majority of patients treated with botulinum neurotoxins (BoNT). In this study, we f...
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Minako Oshima,
Philip R. Deitiker,
Joseph Jankovic,
Drake D. Duane,
K. Roger Aoki,
M. Zouhair Atassi
et al.
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121-128
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Intrathecally synthesized IgG in multiple sclerosis cerebrospinal fluid recognizes identical epitopes over time
14 November 2011
Abstract: Intrathecal antibody production manifest as oligoclonal bands (OCBs) is a hallmark of multiple sclerosis (MS). Once present, OCBs can be detected in CSF throughout the lifetime of MS patient...
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Xiaoli Yu,
Mark Burgoon,
Miyoko Green,
Olga Barmina,
Kathryn Dennison,
Tiffany Pointon,
Molly Davis,
Don Gilden
et al.
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129-136
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| Short Communications |
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Circulating CD8+CD56−perforin+ T cells are increased in multiple sclerosis patients
17 October 2011
Abstract: Relapsing–remitting multiple sclerosis (RRMS), secondary progressive (SP)MS and primary progressive (PP)MS patients showed higher percentages of circulating CD8+CD56−perforin+ T cells than c...
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Frisullo Giovanni,
Plantone Domenico,
Marti Alessandro,
Iorio Raffaele,
Nociti Viviana,
Patanella Agata Katia,
Batocchi Anna Paola
et al.
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137-141
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Blood-borne donor mast cell precursors migrate to mast cell-rich brain regions in the adult mouse
24 October 2011
Abstract: Mast cells are hematopoietic immune cells located throughout the body, including within the brain. Reconstitution of mast cell deficient KitW-sh/W-sh mice has proven valuable in determining ...
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Katherine M. Nautiyal,
Charles Liu,
Xin Dong,
Rae Silver
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142-146
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Opposite effects of interferon-beta on new B and T cell release from production sites in multiple sclerosis patients
14 November 2011
Abstract: The release of newly produced B and T lymphocytes from the production sites was analyzed in 30 multiple sclerosis patients treated with interferon-beta by measuring T-cell receptor excision ...
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Cinzia Zanotti,
Marco Chiarini,
Federico Serana,
Ruggero Capra,
Mariarosa Rottoli,
Marco Rovaris,
Guido Cavaletti,
Raffaella Clerici,
Monica Rezzonico,
Luigi Caimi,
Luisa Imberti
et al.
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147-150
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| Obituary |
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Hillel Panitch, MD
10 November 2011
Hillel Panitch, Professor of Neurology and Director of the Multiple Sclerosis Center at the University of Vermont died on December 23, 2010 at the age of 70 after a year-long battle with melanoma. He ...
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Suhayl Dhib-Jalbut,
Christopher Bever
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151
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| Erratum |
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Erratum to “Time-dependent in-vivo effects of interleukin-2 on neurotransmitters in various cortices: Relationships with depressive-related and anxiety-like behavior” [J. Neuroimmunol. 237(2011)23–32]
21 November 2011
The publisher regrets that during the publication of the above paper Figure 2 was published incorrectly. The updated Figure 2 is reproduced correctly below:
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B.D. Karrenbauer,
C.P. Müller,
Y.J. Ho,
R. Spanagel,
J.P. Huston,
R.K.W. Schwarting,
C.R. Pawlak
et al.
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152-153
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