| |
Article Title |
Author(s) |
Pages |
|
|
|
Editorial Board
|
|
iii
|
|
| Reviews |
| |
Article Title |
Author(s) |
Pages |
|
|
|
Targeting Toll-like receptors: Emerging therapeutics for multiple sclerosis management
05 September 2011
Abstract: Toll-like receptors (TLR) are important innate immune proteins for the identification and clearance of invading pathogen. TLR signal through adaptor proteins, most commonly myeloid different...
|
M. Gambuzza,
N. Licata,
E. Palella,
D. Celi,
V. Foti Cuzzola,
D. Italiano,
S. Marino,
P. Bramanti
et al.
|
1-12
|
|
|
|
Role of glial cells in innate immunity and their role in CNS demyelination
12 September 2011
Abstract: The adaptive and innate arms of the immune system are the two pillars of host defense against environmental pathogens. Multiple sclerosis (MS) is an inflammatory demyelinating disease of the...
|
Subramaniam Sriram
|
13-20
|
|
|
|
Immune-mediated myelitis associated with Hepatitis virus infections
26 September 2011
Abstract: Virus-induced spinal cord damage results from a cytolytic effect on anterior horn cells or from predominantly cellular immune-mediated damage of long white matter tracts. Infection with the ...
|
Joerg-Patrick Stübgen
|
21-27
|
|
| Research Papers |
| |
Article Title |
Author(s) |
Pages |
|
|
|
Neuroadaptive changes in cerebellar neurons induced by chronic exposure to IL-6
05 September 2011
Abstract: IL-6 is an important signaling molecule in the CNS. CNS neurons express IL-6 receptors and their signal transduction molecules, consistent with a role for IL-6 in neuronal physiology. Resear...
|
D.L. Gruol,
A. Puro,
C. Hao,
P. Blakely,
E. Janneke,
K. Vo
et al.
|
28-36
|
|
|
|
Role of α7 nicotinic acetylcholine receptors in regulating tumor necrosis factor-α (TNF-α) as revealed by subtype selective agonists
12 September 2011
Abstract: Immunological responses to protect against excessive inflammation can be regulated by the central nervous system through the cholinergic anti-inflammatory pathway wherein acetylcholine relea...
|
Jinhe Li,
Suzanne L. Mathieu,
Richard Harris,
Jianguo Ji,
David J. Anderson,
John Malysz,
William H. Bunnelle,
Jeffrey F. Waring,
Kennan C. Marsh,
Anwar Murtaza,
Lisa M. Olson,
Murali Gopalakrishnan
et al.
|
37-43
|
|
|
|
Social disruption induced priming of CNS inflammatory response to Theiler's virus is dependent upon stress induced IL-6 release
17 October 2011
Abstract: Chronic social disruption stress (SDR) exacerbates acute and chronic phase Theiler's murine encephalomyelitis virus (TMEV) infection, a mouse model of multiple sclerosis. However, the precis...
|
E.G. Vichaya,
E.E. Young,
M.A. Frazier,
J.L. Cook,
C.J. Welsh,
M.W. Meagher
et al.
|
44-52
|
|
|
|
Prior laparotomy or corticosterone potentiates lipopolysaccharide-induced fever and sickness behaviors
12 September 2011
Abstract: Stimulating sensitized immune cells with a subsequent immune challenge results in potentiated pro-inflammatory responses translating into exacerbated sickness responses (i.e. fever, pain and...
|
Leah E. Hains,
Lisa C. Loram,
Frederick R. Taylor,
Keith A. Strand,
Julie L. Wieseler,
Ruth M. Barrientos,
Jennifer J. Young,
Matthew G. Frank,
Julia Sobesky,
Thomas J. Martin,
James C. Eisenach,
Steven F. Maier,
John D. Johnson,
Monika Fleshner,
Linda R. Watkins
et al.
|
53-60
|
|
|
|
The effects of fasudil on the permeability of the rat blood–brain barrier and blood–spinal cord barrier following experimental autoimmune encephalomyelitis
05 October 2011
Abstract: Dysfunction of the blood–brain barrier (BBB) and blood–spinal cord barrier (BSCB) is a primary characteristic of multiple sclerosis (MS). We evaluated the protective effects of fasudil, a se...
|
X.N. Huang,
J. Fu,
W.Z. Wang
|
61-67
|
|
|
|
Neonatal androgenization affects the efficiency of β-adrenoceptor-mediated modulation of thymopoiesis
23 September 2011
Abstract: We tested the hypothesis that neonatal androgenization affects the efficacy of β-adrenoceptor (β-AR)-mediated fine tuning of thymopoiesis in adult female rats by modulating the thymic noradr...
|
Katarina Radojević,
Duško Kosec,
Milica Perišić,
Ivan Pilipović,
Biljana Vidić-Danković,
Gordana Leposavić
et al.
|
68-79
|
|
| Clinical Neuroimmunology |
| |
Article Title |
Author(s) |
Pages |
|
|
|
Reduction in IL-10 producing B cells (Breg) in multiple sclerosis is accompanied by a reduced naïve/memory Breg ratio during a relapse but not in remission
22 September 2011
Abstract: In this study, we assessed B cell subsets, including Bregs, during stable and active disease in relapsing remitting multiple sclerosis (RRMS) patients and related B cell subsets to vitamin D...
|
Stephanie Knippenberg,
Evelyn Peelen,
Joost Smolders,
Mariëlle Thewissen,
Paul Menheere,
Jan Willem Cohen Tervaert,
Raymond Hupperts,
Jan Damoiseaux
et al.
|
80-86
|
|
|
|
Antibodies to LM1 and LM1-containing ganglioside complexes in Guillain–Barré syndrome and chronic inflammatory demyelinating polyneuropathy
14 September 2011
Abstract: LM1 is localized in human peripheral nerve myelin. Antibodies to ganglioside complexes (GSCs) have been reported in Guillain–Barré syndrome (GBS). We investigated IgG antibodies to LM1 and t...
|
Motoi Kuwahara,
Seiko Suzuki,
Kazuo Takada,
Susumu Kusunoki
|
87-90
|
|
|
|
Anti-neuronal and stress-induced-phosphoprotein 1 antibodies in neuro-Behçet's disease
29 August 2011
Abstract: No disease-specific neuronal antibodies have so far been defined in neuro-Behçet's disease (NBD). Immunohistochemistry and immunocytochemistry studies showed antibodies to hippocampal and ce...
|
Burçak Vural,
Elif Uğurel,
Erdem Tüzün,
Murat Kürtüncü,
Luigi Zuliani,
Filiz Çavuş,
Sema İçöz,
Ece Erdağ,
Ahmet Gül,
Ali O. Güre,
Angela Vincent,
Uğur Özbek,
Mefkure Eraksoy,
Gülşen Akman-Demir
et al.
|
91-97
|
|
| Short Communications |
| |
Article Title |
Author(s) |
Pages |
|
|
|
Mannose binding lectin mediated complement pathway in multiple sclerosis
12 September 2011
Abstract: Role of mannose binding lectin (MBL) complement activation pathway, an arm of innate immunity in multiple sclerosis (MS) was evaluated by analyzing the expression of MBL, MBL-associated seri...
|
Janet Y. Kwok,
Florin Vaida,
Ryan M. Augst,
Denise Y. Yu,
Kumud K. Singh
et al.
|
98-100
|
|
|
|
IL28B polymorphisms are not associated with the response to interferon-beta in multiple sclerosis
02 September 2011
Abstract: Recent studies have revealed an association between interleukin 28B (IL28B) and response to IFN-alpha treatment in hepatitis C patients. Here we investigated the influence of IL28B polymorph...
|
S. Malhotra,
C. Morcillo-Suárez,
D. Brassat,
R. Goertsches,
J. Lechner-Scott,
E. Urcelay,
O. Fernández,
J. Drulovic,
A. García-Merino,
F. Martinelli Boneschi,
A. Chan,
K. Vandenbroeck,
A. Navarro,
M.F. Bustamante,
J. Río,
D.A. Akkad,
G. Giacalone,
A.J. Sánchez,
L. Leyva,
R. Alvarez-Lafuente,
U.K. Zettl,
J. Oksenberg,
X. Montalban,
M. Comabella
et al.
|
101-104
|
|
| Letter to the editor |
| |
Article Title |
Author(s) |
Pages |
|
|
|
Infliximab monotherapy in Neuro-Behçet's disease: Four year follow-up in a long-standing case resistant to conventional therapies
12 September 2011
Behçet's disease (BD) is a vasculitis characterized by hallmark lesions of oral and genital ulcers (). Involvement of parenchymal central nervous system (neuro-BD) is a serious complication commonly c...
|
Alfonso Fasano,
Magda D'Agostino,
Giacomo Caldarola,
Claudio Feliciani,
Clara De Simone
et al.
|
105-107
|
|
