Journal of Neuroimmunology
Volume 221, Issue 1 , Pages 107-111 , 15 April 2010

The TLR7 agonist, imiquimod, increases IFN-β production and reduces the severity of experimental autoimmune encephalomyelitis

  • Kate O'Brien

      Affiliations

    • Division of Clinical Neurology, University of Nottingham, Nottingham, United Kingdom
  • ,
  • Denise Fitzgerald

      Affiliations

    • Centre for Infection and Immunity, Queens University Belfast, Belfast, United Kingdom
  • ,
  • Abdolmohamad Rostami

      Affiliations

    • Department of Neurology, Thomas Jefferson University, Philadelphia, USA
  • ,
  • Bruno Gran

      Affiliations

    • Division of Clinical Neurology, University of Nottingham, Nottingham, United Kingdom
    • Department of Neurology, Thomas Jefferson University, Philadelphia, USA
    • Corresponding Author InformationCorresponding author. Division of Clinical Neurology, University of Nottingham, B31 Medical School, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom. Tel.: +44 115 849 3363.

Received 7 December 2009 ,Revised 12 January 2010 ,Accepted 13 January 2010.

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PII: S0165-5728(10)00011-1

doi: 10.1016/j.jneuroim.2010.01.006

Journal of Neuroimmunology
Volume 221, Issue 1 , Pages 107-111 , 15 April 2010