Journal of Neuroimmunology
Volume 220, Issue 1 , Pages 52-63 , 30 March 2010

Rapamycin inhibits relapsing experimental autoimmune encephalomyelitis by both effector and regulatory T cells modulation

  • Marianna Esposito

      Affiliations

    • Clinical Neuroimmunology Unit, Department of Neuroscience, Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute DIBIT, Milan, Italy
    • ,
  • Francesca Ruffini

      Affiliations

    • Clinical Neuroimmunology Unit, Department of Neuroscience, Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute DIBIT, Milan, Italy
    • ,
  • Matteo Bellone

      Affiliations

    • Department of Oncology, Cancer Immunotherapy and Gene Therapy Program (CIGTP), San Raffaele Scientific Institute DIBIT, Milan, Italy
    • ,
  • Nicola Gagliani

      Affiliations

    • Telethon Institute for Gene Therapy (TIGET), San Raffaele Scientific Institute DIBIT, Milan, Italy
    • ,
  • Manuela Battaglia

      Affiliations

    • Telethon Institute for Gene Therapy (TIGET), San Raffaele Scientific Institute DIBIT, Milan, Italy
    • Diabetes Research Institute (DRI), San Raffaele Scientific Institute DIBIT, Milan, Italy
    • ,
  • Gianvito Martino

      Affiliations

    • Neuroimmunology Unit, Department of Neuroscience, Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute DIBIT, Milan, Italy
    • ,
  • Roberto Furlan

      Affiliations

    • Clinical Neuroimmunology Unit, Department of Neuroscience, Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute DIBIT, Milan, Italy
    • Corresponding Author InformationCorresponding author. Clinical Neuroimmunology Unit, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Via Olgettina 58, 20132 Milano, Italy. Tel.: +39 02 26434867; fax: +39 02 26434855.

Received 26 October 2009 ,Revised 5 January 2010 ,Accepted 5 January 2010.

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PII: S0165-5728(10)00006-8

doi: 10.1016/j.jneuroim.2010.01.001

Journal of Neuroimmunology
Volume 220, Issue 1 , Pages 52-63 , 30 March 2010

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