« Previous
Next »
Journal of Neuroimmunology
Volume 217, Issue 1
, Pages 65-73
, 10 December 2009
Autoantibodies to the δ-opioid receptor function as opioid agonists and display immunomodulatory activity
References
- . Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death. Proc. Natl. Acad. Sci. U. S. A. 2007;104:14104–14109
- . Release of cytokines, soluble cytokine receptors, and interleukin-1 receptor antagonist after intravenous immunoglobulin administration in vivo. Blood. 1994;84:2136–2143
- . Delta opioid receptors mediate chemotaxis in bone marrow-derived dendritic cells. J. Neuroimmunol. 2008;197:21–28
- . Detection and function of opioid receptors on cells from the immune system. Clin. Diagn. Lab. Immunol. 2000;7:719–723
- . The efficacy of specific IVIG anti-idiotypic antibodies in antiphospholipid syndrome (APS): trophoblast invasiveness and APS animal model. Int. Immunol. 2007;19:857–865
- . Natural mucosal antibodies reactive with first extracellular loop of CCR5 inhibit HIV-1 transport across human epithelial cells. AIDS. 2007;21:13–22
- . Antibodies to C–C chemokine receptor 5 in normal human IgG block infection of macrophages and lymphocytes with primary R5-tropic strains of HIV-1. J. Immunol. 2001;166:7606–7611
- . Natural antibodies to CCR5 from breast milk block infection of macrophages and dendritic cells with primary R5-tropic HIV-1. J. Immunol. 2005;174:7202–7209
- . Heterodimerization and cross-desensitization between the mu-opioid receptor and the chemokine CCR5 receptor. Eur. J. Pharmacol. 2004;483:175–186
- . Implication of the first and third extracellular loops of the mu-opioid receptor in the formation of the ligand binding site: a study using chimeric mu-opioid/angiotensin receptors. J. Neurochem. 1998;70:2106–2111
- . Immunomodulation of human B cells following treatment with intravenous immunoglobulins involves increased phosphorylation of extracellular signal-regulated kinases 1 and 2. Int. Immunol. 2008;20:1369–1379
- . Expansion of CD4+CD25+ regulatory T cells by intravenous immunoglobulin: a critical factor in controlling experimental autoimmune encephalomyelitis. Blood. 2008;111:715–722
- . Infection of macrophages and dendritic cells with primary R5-tropic human immunodeficiency virus type 1 inhibited by natural polyreactive anti-CCR5 antibodies purified from cervicovaginal secretions. Clin. Vaccine Immunol. 2008;15:872–884
- . Exploring deltorphin II binding to the third extracellular loop of the delta-opioid receptor. J. Biol. Chem. 2004;279:21069–21077
- . Bi-directional heterologous desensitization between the major HIV-1 co-receptor CXCR4 and the kappa-opioid receptor. J. Neuroimmunol. 2008;197:114–123
- . Opioid and nociceptin receptors regulate cytokine and cytokine receptor expression. Cell. Immunol. 2008;252:146–154
- . Chronic morphine treatment promotes specific Th2 cytokine production by murine T cells in vitro via a Fas/Fas ligand-dependent mechanism. J. Immunol. 2005;175:4999–5005
- . Opiates transdeactivate chemokine receptors: delta and mu opiate receptor-mediated heterologous desensitization. J. Exp. Med. 1998;188:317–325
- . DAMGO-induced expression of chemokines and chemokine receptors: the role of TGF-beta1. J. Leukoc. Biol. 2008;83:956–963
- . Advances in the understanding of the mechanism of action of IVIg. J. Neurol. 2008;255(Suppl 3):3–6
- . Opioid and chemokine receptor heterodimers: arranged marriages or dangerous liaisons?. Biochem. J. 2008;412:e7–e9
- . Slamming the DOR on chemokine receptor signaling: heterodimerization silences ligand-occupied CXCR4 and delta-opioid receptors. Eur. J. Immunol. 2008;38:334–337
- . A comparative study of immunomodulation produced by in vitro exposure to delta opioid receptor agonist peptides. Peptides. 1996;17:75–81
- . Anti-CD4 activity of normal human immunoglobulin G for therapeutic use. (Intravenous immunoglobulin, IVIg). Ther. Immunol. 1994;1:269–277
- . Opioid receptor blockade increases the number of lymphocytes without altering T cell response in draining lymph nodes in vivo. J. Neuroimmunol. 2007;188:95–102
- . Antibodies to a conserved region of HLA class I molecules, capable of modulating CD8 T cell-mediated function, are present in pooled normal immunoglobulin for therapeutic use. J. Clin. Invest. 1996;97:865–869
- . Immunomodulation of autoimmune and inflammatory diseases with intravenous immune globulin. N. Engl. J. Med. 2001;345:747–755
- . Intravenous immunoglobulin therapy affects T regulatory cells by increasing their suppressive function. J. Immunol. 2007;179:5571–5575
- . delta-Opioid receptor: the third extracellular loop determines naltrindole selectivity. Eur. J. Pharmacol. 1996;300:R1–R2
- . Isolation and characterization of natural human IgG with a morphine-like activity. Eur. J. Immunol. 1999;29:997–1003
- . Morphine-like activity of natural human IgG autoantibodies is because of binding to the first and third extracellular loops of the mu-opioid receptor. J. Biol. Chem. 1999;274:20079–20082
- . Identification of mu-opioid receptor epitopes recognized by agonistic IgG. Biochem. Biophys. Res. Commun. 2001;280:1142–1147
- . Anti-mu-opioid-receptor IgG antibodies are commonly present in serum from healthy blood donors: evidence for a role in apoptotic immune cell death. Blood. 2002;100:3261–3268
- . Human autoantibodies reactive with synthetic autoantigens from T-cell receptor beta chain. Proc. Natl. Acad. Sci. U. S. A. 1992;89:3325–3329
- . Opioids, opioid receptors, and the immune response. Drug Alcohol Depend. 2001;62:111–123
- . Evidence for central opioid receptors in the immunomodulatory effects of morphine: review of potential mechanism(s) of action. J. Neuroimmunol. 1998;83:19–28
- . delta opioid receptor expression is induced by concanavalin A in CD4+ T cells. J. Immunol. 1996;157:5324–5328
- . Morphine induces gene expression of CCR5 in human CEMx174 lymphocytes. J. Biol. Chem. 2000;275:31305–31310
- . Morphine promotes phosphorylation of the human delta-opioid receptor at serine 363. Eur. J. Pharmacol. 2005;519:212–214
- . Intravenous immunoglobulin: an update on the clinical use and mechanisms of action. J. Clin. Immunol. 2007;27:233–245
- . CD28 costimulation induces delta opioid receptor expression during anti-CD3 activation of T cells. J. Immunol. 2002;168:4440–4445
- . Ligand stabilization of CXCR4/delta-opioid receptor heterodimers reveals a mechanism for immune response regulation. Eur. J. Immunol. 2008;38:537–549
- . The opioid-cytokine connection. J. Neuroimmunol. 1998;83:63–69
- . Therapeutic preparations of normal polyspecific IgG (IVIg) induce apoptosis in human lymphocytes and monocytes: a novel mechanism of action of IVIg involving the Fas apoptotic pathway. J. Immunol. 1998;161:3781–3790
- . The natural autoantibody repertoire and autoimmune disease. Biomed. Pharmacother. 2004;58:276–281
- . Variation of anti-Fas antibodies in different lots of intravenous immunoglobulin. Vox Sang. 2008;94:334–341
- . Bidirectional heterologous desensitization of opioid and chemokine receptors. Ann. N. Y. Acad. Sci. 2000;917:19–28
- . Chronic morphine treatment differentiates T helper cells to Th2 effector cells by modulating transcription factors GATA 3 and T-bet. J. Neuroimmunol. 2004;147:78–81
- . Modulation of immune function by morphine: implications for susceptibility to infection. J. Neuroimmune Pharmacol. 2006;1:77–89
- . Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids. Immunogenetics. 1985;21:235–246
- . Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor. Science. 2001;291:484–486
- . What is the contents of the magic draft IVIg?. Autoimmun Rev. 2008;7:435–439
- . Expression of delta opioid receptors by splenocytes from SEB-treated mice and effects on phosphorylation of MAP kinase. Cell. Immunol. 2000;205:84–93
- . Phosphorylation of activating transcription factor in murine splenocytes through delta opioid receptors. Cell. Immunol. 2003;221:122–127
- . delta opioid receptors stimulate Akt-dependent phosphorylation of c-jun in T cells. J. Pharmacol. Exp. Ther. 2006;316:933–939
- . Opioid receptor expression and function. J. Neuroimmunol. 2004;147:3–5
- . Multiple opioid receptors on immune cells modulate intracellular signaling. Brain Behav. Immun. 2006;20:9–14
- . Delta-opioid suppression of human immunodeficiency virus-1 expression in T cells (Jurkat). Biochem. Pharmacol. 1998;56:289–292
- . Signaling through delta opioid receptors on murine splenic T cells and stably transfected Jurkat cells. Ann. N. Y. Acad. Sci. 1998;840:420–424
- . Evidence for opioid receptors on cells involved in host defense and the immune system. J. Neuroimmunol. 1998;83:45–56
- . Immunofluorescence detection of delta opioid receptors (DOR) on human peripheral blood CD4+ T cells and DOR-dependent suppression of HIV-1 expression. J. Immunol. 2001;167:1097–1102
- . Kappa and delta opioid receptors are expressed but down-regulated in fibroblast-like synoviocytes of patients with rheumatoid arthritis and osteoarthritis. Arthritis Rheum. 2005;52:1402–1410
- . Protective autoantibodies: role in homeostasis, clinical importance, and therapeutic potential. Arthritis Rheum. 2005;52:2599–2606
- . Efficacy of IVIG affinity-purified anti-double-stranded DNA anti-idiotypic antibodies in the treatment of an experimental murine model of systemic lupus erythematosus. Int. Immunol. 2002;14:1303–1311
- . Interactions between opioid and chemokine receptors: heterologous desensitization. Cytokine Growth Factor Rev. 2002;13:209–222
- . Mu-opioid modulation of HIV-1 coreceptor expression and HIV-1 replication. Virology. 2003;309:99–107
- . Interactions of opioid and chemokine receptors: oligomerization of mu, kappa, and delta with CCR5 on immune cells. Exp. Cell Res. 2002;280:192–200
- . Antibody to granulocyte-macrophage colony-stimulating factor is a dominant anti-cytokine activity in human IgG preparations. Blood. 1998;91:2054–2061
- . Selective inactivation of CCR5 and decreased infectivity of R5 HIV-1 strains mediated by opioid-induced heterologous desensitization. J. Leukoc. Biol. 2003;74:1074–1082
- . Opioids as modulators of cell death and survival-unraveling mechanisms and revealing new indications. Pharmacol. Rev. 2004;56:351–369
- . Opioid therapy and immunosuppression: a review. Am. J. Ther. 2004;11:354–365
- . Role of natural antibodies in immune homeostasis: IVIg perspective. Autoimmun. Rev. 2008;7:440–444
- . The third extracellular loop of the human delta-opioid receptor determines the selectivity of delta-opioid agonists. Mol. Pharmacol. 1996;50:1619–1624
- . Involvement of Raf-1 in chronic delta-opioid receptor agonist-mediated adenylyl cyclase superactivation. Eur. J. Pharmacol. 2002;451:101–102
- . Agonist-specific regulation of the delta-opioid receptor. Life Sci. 2004;76:599–612
- . Antibodies to the CD5 molecule in normal human immunoglobulins for therapeutic use (intravenous immunoglobulins, IVIg). Clin. Exp. Immunol. 1993;92:369–372
- . Inhibition of cell adhesion by antibodies to Arg-Gly-Asp (RGD) in normal immunoglobulin for therapeutic use (intravenous immunoglobulin, IVIg). Blood. 1999;93:3624–3631
- . Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin. Science. 1998;282:490–493
- . Natural anti-Siglec autoantibodies mediate potential immunoregulatory mechanisms: implications for the clinical use of intravenous immunoglobulins (IVIg). Autoimmun. Rev. 2008;7:453–456
- . Cellular and synaptic adaptations mediating opioid dependence. Physiol. Rev. 2001;81:299–343
PII: S0165-5728(09)00399-3
doi: 10.1016/j.jneuroim.2009.10.007
© 2009 Elsevier B.V. All rights reserved.
« Previous
Next »
Journal of Neuroimmunology
Volume 217, Issue 1
, Pages 65-73
, 10 December 2009
