Journal of Neuroimmunology
Volume 217, Issue 1 , Pages 10-11 , 10 December 2009

Protective and therapeutic effect of triptolide in EAE explained by induction of major stress protein HSP70

Received 14 September 2009 ,Accepted 14 September 2009.

References 

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  2. Fu YF, Zhu YN, Ni J, Zhong XG, Tang W, Zhou R, et al. (5R)-5-hydroxytriptolide (LLDT-8), a novel triptolide derivative, prevents experimental autoimmune encephalomyelitis via inhibiting T cell activation. J. Neuroimmunol. 2006;175:142–151
  3. Kizelsztein P, Komarnytsky S, Raskin I. Oral administration of triptolide ameliorates the clinical signs of experimental autoimmune encephalomyelitis (EAE) by induction of HSP70 and stabilization of NF-κB/IκBα transcriptional complex. J. Neuroimmunol. 2009;217:28–37(this issue)
  4. Kitamei H, Kitaichi N, Yoshida K, Nakai A, Fujimoto M, Kitamura M, et al. Association of heat shock protein 70 induction and the amelioration of experimental autoimmune uveoretinitis in mice. Immunobiology. 2007;212:11–18
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  13. Zhang JF, Huang R, Xu J, Jin SJ, Yang YJ. Protective effects of heat shock preconditioning on the experimental autoimmune encephalomyelitis rats. Zhongguo Dang Dai Er Ke Za Zhi. 2007;9:563–566

PII: S0165-5728(09)00354-3

doi: 10.1016/j.jneuroim.2009.09.008

Journal of Neuroimmunology
Volume 217, Issue 1 , Pages 10-11 , 10 December 2009

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